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 Friday, March 28, 2008

By Daniel Herbster

When I first read recent media reports about research which seemed to indicate mice with Parkinson’s disease were successfully treated using a form of cloning called somatic cell nuclear transfer (SCNT), I was skeptical.  But even if the media reports of success were correct, it still would not make SCNT ethical for use in humans because it would amount to cloning and killing human beings (embryos).  I wanted get an expert opinion on the actual science behind the reports so I contacted Dr. David Prentice whom I’ve had the privilege to hear speak and meet on several occasions.

Reinforced my concerns with the unethical nature of the research if it were ever tried in humans, Dr. Prentice told me…

…the whole idea of so-called "therapeutic cloning" is unethical on several levels.  It requires creating and destroying an embryo, a young life.  It also requires a tremendous number of eggs to make just one dish of cells, so it risks women's health, making them factories for raw parts for the experiments.

Dr. Prentice also mentioned three crucial points the reports neglected to point out.

  • 1 out of every 6 mice showed "graft overgrowth".  In other words, the implanted embryonic stem cells grew too well.
  • They only let the animals go for 11 weeks, so we don't know if they would have gone on to form tumors, or if the treatment has any lasting effect.
  • The technique is also already outdated.  The paper was originally submitted in Feb 2007, long before most of the results with iPS cells [induced pluripotent stem cells].  So the science has already passed this by, with easier, ethical, and successful procedures.

Thank you Dr. Prentice for sharing your expertise with us.  Find out more about Dr. Prentice’s work at FRC.org and at DoNoHarm.


Dr. David Prentice
Graphic source: FRC

Click here for more information on human cloning, and click here for more information on embryonic stem cell research.